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accession-icon DRP002695
Transcriptome analysis of HSCs and leukemic spleens (Ly6A/Sca-1 Fbxl10 Tg vs Ctrl)
  • organism-icon Mus musculus
  • sample-icon 9 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer IIx

Description

Ly6A/Sca-1 Fbxl10 Tg mice develop myeloid and B-cell leukemia with complete penetrance. (Ueda et al.,Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2, PMID 25872778)

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

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accession-icon DRP002858
Transcriptome analysis of neuronal cells and MYCN-induced neuroblastomas (ALK WT vs ALK R1275Q)
  • organism-icon Mus musculus
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer IIx

Description

An activating mutation of ALK, ALK R1275Q was idenftified in neuroblastoma. ALK R1275Q knock-in/MYCN transgenic mice developed invasive and metastatic neuroblastoma with complete penetrance, coupled with decreased extracellular matrix/basement membrane components.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

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accession-icon DRP002819
RNA-seq analysises of iMEFs
  • organism-icon Mus musculus
  • sample-icon 5 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer IIx

Description

An Immrtalized mouse embryonic fibroblast cell line (iMEF) was transduced with shRNA expression vectors and subjected for RNA-seq anaysis. Taf1c was knocked down by two different shRNAs. Enl and Mll were knocked down by single shRNA. RNAs were reverse-transcribed and subjected to deep sequencing along with the vector control sample (pLKO.1)

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Cell line

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accession-icon DRP003183
Eed conditional heterozygous HSC RNA-seq
  • organism-icon Mus musculus
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Transcriptome analysis of hematopoietic stem cells [HSC (LSK)] (Eed cKO (flox/+ ERT2Cre+) vs control (flox/+ ERT2Cre-), 1 month post-tamoxifen injection, from 7 males and 4 females for each group

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon DRP003489
c-Cbl Q367P HSC RNA-seq
  • organism-icon Mus musculus
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer IIx

Description

Transcriptome analysis of Hematopoietic stem cells [HSC (LSK)] (Ctrl (flox/flox, MxCre-) vs cKI (Q367P)(flox/flox, MxCre+), 3 months post pIpC injection

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon DRP003182
Eed cKO HSC RNA-seq
  • organism-icon Mus musculus
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer IIx

Description

Transcriptome analysis of hematopoietic stem cells [HSC (LSK)] (Eed cKO (flox/flox ERT2Cre+) vs control (flox/flox ERT2Cre-). Mice were injected with tamoxifen for five consecutive days and then sacrificed two days after the final injection.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon DRP003243
Eed I363M HSC RNA-seq
  • organism-icon Mus musculus
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer IIx

Description

Transcriptome analysis of hematopoietic stem cells [HSC (LSK; Lin-, c-Kit+, Sca-1+ bone marrow cells)] (Eed I363M/+ vs Eed +/+) (males, 11-14 weeks of age)

Publication Title

No associated publication

Sample Metadata Fields

Sex, Cell line

View Samples
accession-icon DRP000667
Comprehensive identification and characterization of the WT mouse bonemarrow LSK transcriptome
  • organism-icon Mus musculus
  • sample-icon 1 Downloadable Sample
  • Technology Badge IconIllumina Genome Analyzer IIx

Description

Comprehensive identification and characterization of the WT mouse bonemarrow LSK transcriptome were attempted. We used RNA-seq.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon DRP000669
Comprehensive identification and characterization of the Titan hetero mouse bonemarrow LSK transcriptome
  • organism-icon Mus musculus
  • sample-icon 1 Downloadable Sample
  • Technology Badge IconIllumina Genome Analyzer IIx

Description

Comprehensive identification and characterization of the Titan hetero mouse bonemarrow LSK transcriptome were attempted. We used RNA-seq.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon DRP000668
Comprehensive identification and characterization of the Titan homo mouse bonemarrow LSK transcriptome
  • organism-icon Mus musculus
  • sample-icon 1 Downloadable Sample
  • Technology Badge IconIllumina Genome Analyzer IIx

Description

Comprehensive identification and characterization of the Titan homo mouse bonemarrow LSK transcriptome were attempted. We used RNA-seq.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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