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Accession IconDRP002695

Transcriptome analysis of HSCs and leukemic spleens (Ly6A/Sca-1 Fbxl10 Tg vs Ctrl)

Organism Icon Mus musculus
Sample Icon 9 Downloadable Samples
Technology Badge IconIllumina Genome Analyzer IIx

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Description
Ly6A/Sca-1 Fbxl10 Tg mice develop myeloid and B-cell leukemia with complete penetrance. (Ueda et al.,Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2, PMID 25872778)
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