Transcriptome analysis of neuronal cells and MYCN-induced neuroblastomas (ALK WT vs ALK R1275Q)

DRP002858

Mus musculus

8 Downloadable Samples

Illumina Genome Analyzer IIx

Submitter Supplied Information

Description

An activating mutation of ALK, ALK R1275Q was idenftified in neuroblastoma. ALK R1275Q knock-in/MYCN transgenic mice developed invasive and metastatic neuroblastoma with complete penetrance, coupled with decreased extracellular matrix/basement membrane components.

PubMed ID

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Publication Title

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Total Samples

Submitter’s Institution

Radiation Research Center for Frontier Science Facilities for Gene Technology, Research Institute for Radiation Biology and Medicine, Hiroshima University

Authors

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Source Repository

Sequence Read Archive (SRA)

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