This SuperSeries is composed of the SubSeries listed below.
Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis.
Sex, Specimen part
View SamplesCharacterisation of blood and lung global transcriptional responses to Mycobacterium tuberculosis infection in distinct mouse models of Tuberculosis
Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis.
No sample metadata fields
View SamplesCharacterisation of blood and lung global transcriptional responses to Mycobacterium tuberculosis infection in distinct mouse models of Tuberculosis
Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis.
No sample metadata fields
View SamplesAcute myeloid leukemia remodels the bone marrow non-hematopoietic microenvironment which disrupts niche archiecture and normal hematopoiesis The precise interactions underlying this process are not well understood
No associated publication
Specimen part, Cell line
View SamplesWe report the expression anaysis of neural stem cells lacking p53, ATMIN, or both. p53-deficent cells form GBM, which is significanly delayed in the absence of ATMIN.
Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation.
Specimen part
View SamplesAsthma arises from the complex interplay of inflammatory pathways in diverse cell types and tissues including epithelial and T cells.
Multitissue Transcriptomics Delineates the Diversity of Airway T Cell Functions in Asthma.
Sex, Subject
View SamplesManagement of severe asthma remains a challenge despite treatment with glucocorticosteroid therapy. The majority of studies investigating disease mechanisms in treatment-resistant severe asthma have previously focused on the large central airways, with very few utilizing transcriptomic approaches. The small peripheral airways, which comprise the majority of the airway surface area, remain an unexplored area in severe asthma and were targeted for global epithelial gene expression profiling in this study.
Altered Epithelial Gene Expression in Peripheral Airways of Severe Asthma.
Sex, Age, Specimen part, Disease, Subject
View SamplesThis SuperSeries is composed of the SubSeries listed below.
UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene.
Cell line, Treatment, Time
View SamplesTotal RNA was isolated from liver samples of C57/BL6 mice over a circadian time course, 3 biological replicate samples per time point were collected and processed individually. RNA from each individual biological replicate sample was extracted using RNeasy mini kit (Qiagen Cat# 74106) and hybridized on an Affymetrix mouse Gene ST1.0 microarray.
Histone methyltransferase MLL3 contributes to genome-scale circadian transcription.
Specimen part, Time
View SamplesIntegration of multi-omics data remains a key challenge in fulfilling the potential of comprehensive systems biology.
OnPLS-Based Multi-Block Data Integration: A Multivariate Approach to Interrogating Biological Interactions in Asthma.
Sex, Age, Specimen part, Disease, Disease stage
View Samples