Cxcr7-/- mice die a few hours after birth. All of them display semilunar valves abnormalities, including bicuspid aortic or pulmonary valves. Those defects only become obvious before birth.
Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7.
No sample metadata fields
View SamplesRNA sequencing of FACS-purified Cd4+ and Cd8+ T cells from 8 weeks old female wt C57BL/6 mouse spleens
No associated publication
No sample metadata fields
View SamplesThis study aims to compare the global expression signature of protein coding genes between oral cancers from carcinogen-induced mice and human patients. Combinatorial treatment of 4NQO and arecoline for 8 weeks consistently induced the formation of mouse oral cancer with morphology and pathology resembling human oral squamous cell carcinoma. In this dataset, 5 mouse normal tongue and 7 tumor samples were used and Illumina Mouse Ref-8 cDNA microarray was conducted.
No associated publication
Age, Specimen part
View SamplesTo explore the molecular functions targeted by these miRNAs, we classified genes differentially expressed in clinical HCC samples into six functional clusters based on their functional similarity.
Identification of a two-layer regulatory network of proliferation-related microRNAs in hepatoma cells.
Specimen part
View SamplesDisabled-2 (DAB2) is up-regulated when ESC were cocultured with OP9 stromal cells for mesodermal colony formation. Expression of DAB2 short hairpin small interfering RNA (shDAB2) altered ESC cell-cell adhesion that subsequently affected colony formation and mesoderm differentiation competence.
No associated publication
Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma.
Disease, Disease stage
View SamplesIn order to aid the development of patient-tailored diagnostics and therapeutics, we attempted to identify a genetic signature associated with disease prognosis in OSCC. A genome-wide analysis of transcription with the Affymetrix GeneChip Human Gene 1.0 ST Array was conducted.
A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma.
Disease, Disease stage
View SamplesComparison of the gene expression profiles with meningiomas of different grading.
No associated publication
Specimen part, Disease stage
View SamplesThis SuperSeries is composed of the SubSeries listed below.
No associated publication
Specimen part
View SamplesThe underlying change of gene network expression of Guillain-Barre syndrome (GBS) remains elusive. We sought to identify GBS-associated gene networks and signalling pathways by analyzing the transcriptional profile of leukocytes in the patients with GBS.
Identification of gene networks and pathways associated with Guillain-Barré syndrome.
Sex, Age, Specimen part, Race
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