Using mouse lung resident conventional CD11b+ dendritic cells (CD11b+ cDCs) in the context of house-dust mite (HDM)-driven allergic airway sensitization as a model, we aimed here to identify transcriptional events regulating the pro-Th2 activity of cDCs.
Interferon response factor-3 promotes the pro-Th2 activity of mouse lung CD11b<sup>+</sup> conventional dendritic cells in response to house dust mite allergens.
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