This SuperSeries is composed of the SubSeries listed below.
Alteration of Gene Expression, DNA Methylation, and Histone Methylation in Free Radical Scavenging Networks in Adult Mouse Hippocampus following Fetal Alcohol Exposure.
Sex, Specimen part, Treatment
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Identification of interactive networks of gene expression associated with osteosarcoma oncogenesis by integrated molecular profiling.
Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
In vitro analysis of integrated global high-resolution DNA methylation profiling with genomic imbalance and gene expression in osteosarcoma.
No sample metadata fields
View SamplesGain or loss of genes and deregulation of gene expression can result in cumulative and progressive disruptions of normal cellular functions.
Identification of interactive networks of gene expression associated with osteosarcoma oncogenesis by integrated molecular profiling.
Specimen part
View SamplesGain or loss of genes and deregulation of gene expression can result in cumulative and progressive disruptions of normal cellular functions.
In vitro analysis of integrated global high-resolution DNA methylation profiling with genomic imbalance and gene expression in osteosarcoma.
No sample metadata fields
View SamplesThis SuperSeries is composed of the SubSeries listed below.
No associated publication
Sex, Age, Treatment, Race
View SamplesThe objective of this study was to examine relationships between weight loss through changes in lifestyle and peripheral blood gene expression profiles. Substantial weight loss (-15.2+3.8%) in lifestyle participants was associated with improvement in selected cardiovascular risk factors and significant changes in peripheral blood gene expression from pre- to post-intervention: 132 unique genes showed significant expression changes related to immune function and inflammatory responses involving endothelial activation.
Importance of substantial weight loss for altering gene expression during cardiovascular lifestyle modification.
Sex, Age, Specimen part
View SamplesBackground: Obesity is a risk factor for breast cancer in postmenopausal women and is associated with decreased survival and less favorable clinical characteristics such as greater tumor burden, higher grade, and poor prognosis, regardless of menopausal status. Despite the negative impact of obesity on clinical outcome, molecular mechanisms through which excess adiposity influences breast cancer etiology are not well-defined.
Effect of obesity on molecular characteristics of invasive breast tumors: gene expression analysis in a large cohort of female patients.
Disease stage
View SamplesIntensive lifestyle modification is believed to mediate cardiovascular disease (CVD) risk through traditional pathways that affect endothelial function and progression of atherosclerosis; however, the extent, persistence, and clinical significance of molecular change during lifestyle modification are not well known. Our study reveals that gene expression signatures are significantly modulated by rigorous lifestyle behaviors and track with CVD risk profiles over time.
Intensive cardiovascular risk reduction induces sustainable changes in expression of genes and pathways important to vascular function.
Sex, Age
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Master regulators of FGFR2 signalling and breast cancer risk.
Specimen part, Cell line
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