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Mus musculus
12 Downloadable Samples
Illumina HiSeq 1500
Description
Transcriptome of E14.5, E18.5, P10, P21 and P56 fetal Leydig cells and adult Leydig cells in mouse testis.
Publication Title
No associated publication
Sample Metadata Fields
Specimen part
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DRP001160- Mus musculus
- 5 Downloadable Samples
- Illumina Genome Analyzer IIx
Description
RNA-seq analysis using adult Leydig cells were performed.
Publication Title
No associated publication
Sample Metadata Fields
No sample metadata fields
View Samples- Mus musculus
- 5 Downloadable Samples
- Illumina Genome Analyzer IIx, Illumina HiSeq 1000
Description
RNA profiles of fetal Leydig cells (S-EGFP), interstitial cells (W-EGFP), and Sertoli cells in E16.5 mouse testis
Publication Title
No associated publication
Sample Metadata Fields
Specimen part
View Samples- Mus musculus
- 4 Downloadable Samples
- Illumina Genome Analyzer IIx
Description
RNA profiles of XY and XX/Sry Sertoli cells, isolated from postnatal day 1 (P1) and P21 mouse testes.
Publication Title
No associated publication
Sample Metadata Fields
Specimen part
View Samples- Mus musculus
- 3 Downloadable Samples
- Illumina HiSeq 1500
Description
Identification of genes regulated by transcription factor, Ad4BP/SF-1 or Srebf2 in adrenal cortex-derived cell line by RNA-sequence.
Publication Title
No associated publication
Sample Metadata Fields
Cell line
View Samples DRP000884- Mus musculus
- 2 Downloadable Samples
- Illumina Genome Analyzer IIx
Description
To find direct or indirect targets of Ad4BP/SF-1, RNA profiles of Y-1 cells were obtained with or without siRNA for Ad4BP/SF-1.
Publication Title
Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1.
Sample Metadata Fields
No sample metadata fields
View Samples- Rattus norvegicus
- 7 Downloadable Samples
Affymetrix Rat Genome 230 2.0 Array (rat2302)
Description
The application of mechanical insults to the spinal cord results in profound cellular and molecular changes, including the induction of neuronal cell death and altered gene expression profiles. We demonstrated that spinal cord cells undergo cell death in response to cyclic tensile stresses, which were dose- and time- dependent. In addition, we have identified the up regulation of various genes, in particular of the MAPK pathway, which may be involved in this cellular response.
Publication Title
Microarray analysis of expression of cell death-associated genes in rat spinal cord cells exposed to cyclic tensile stresses in vitro.
Sample Metadata Fields
Specimen part
View Samples- Xenopus laevis
- 4 Downloadable Samples
- Affymetrix Xenopus laevis Genome Array (xenopuslaevis)
Description
Xenopus laevis embryos were injected with alpha-amanitin to inhibit RNA polymerase II activity. Embryos were allowed to develop up to stage 10.5 (early gastrula, control and alpha-amanitin injected embryos) and subsequently collected for RNA isolation. The transcriptome profiles of alpha-amanitin injected and control embryos were compared.
Publication Title
Robust activation of a Tbox-Gsc-Otx2 gene network independent of TATA binding protein family members
Sample Metadata Fields
Compound
View Samples- Mus musculus
- 5 Downloadable Samples
- Affymetrix Mouse Gene 2.0 ST Array (mogene20st)
Description
Appropriate regulation of hematopoietic stem cell (HSC) self-renewal is critical for the maintenance of life long hematopoiesis. However, long-term repeated cell divisions induce the accumulation of DNA damage, especially at telomere, significantly compromises HSC function. Therefore, shelterin elements Pot1a is required to prevent DNA damage response at telomeres in order to maintain their function.
Publication Title
The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age.
Sample Metadata Fields
Sex, Specimen part
View Samples- Mus musculus
- 2 Downloadable Samples
- Affymetrix Mouse Gene 2.0 ST Array (mogene20st)
Description
Appropriate regulation of hematopoietic stem cell (HSC) self-renewal is critical for the maintenance of life long hematopoiesis. However, long-term repeated cell divisions induce the accumulation of DNA damage, especially at telomere, significantly compromises HSC function. Therefore, shelterin elements Pot1a is required to prevent DNA damage response at telomeres in order to maintain their function.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part
View Samples