Expression profiling of MRC5, IFN gamma treated MRC5 and PGF cells.
Reconfiguration of genomic anchors upon transcriptional activation of the human major histocompatibility complex.
No sample metadata fields
View SamplesIt has been shown that tumor infiltrating immune cells have a profound impact on the outcome of FL. To find mechanisms whereby TILs are altered gene expession analysis of highly pure TILs were performed.
Follicular lymphoma cells induce changes in T-cell gene expression and function: potential impact on survival and risk of transformation.
Specimen part, Subject
View SamplesEnvironmental enrichment has been shown to induce wholescale alterations to the gene expression profile of experimental animals
The impact of environmental enrichment on the murine inflammatory immune response.
Sex, Age
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Adult rat bones maintain distinct regionalized expression of markers associated with their development.
Sex, Specimen part, Treatment
View SamplesAnalysis of basal gene expression of the protective bones of the skull (parietals) and weight-bearing bones of the limb (ulnae)
Adult rat bones maintain distinct regionalized expression of markers associated with their development.
Sex, Specimen part, Treatment
View SamplesPilot study
Adult rat bones maintain distinct regionalized expression of markers associated with their development.
Sex, Specimen part
View SamplesObjective: to Identify the effect of surface texture on the modulation of gene transcription of implant adherent cells as influenced by the smoking habits of the subjects.
No associated publication
Specimen part, Subject
View SamplesTo determine the early temporal wide genome transcription regulation by the surface topography at the bone-implant interface of implants bearing micro-roughened or superimposed nanosurface topology.
No associated publication
Sex
View SamplesObjective: to identify the early molecular processes involved in osseointegration associated with a micro roughened and nanosurface featured implants.
Comparative molecular assessment of early osseointegration in implant-adherent cells.
Sex, Specimen part
View SamplesThis study was aimed to identify the genetic contributors to pulpal pain and inflammation. Inflamed pulps were collected from patients diagnosed with irreversible pulpitis (n=6). Normal pulps from teeth extracted for various reasons served as controls (n=6). Pain level was assessed using a visual analog scale (VAS). Genome-wide microarray analysis was performed using Affymetrix GeneTitan Multichannel Instrument. The difference in gene expression levels were determined by the Significance Analysis of Microarray program using a false discovery rate (q-value) of 5%. Genes involved in immune response, cytokine-cytokine receptor interaction and signaling, integrin cell surface interactions, and others were expressed at relatively higher levels in the pulpitis group. Moreover, several genes known to modulate pain and inflammation showed differential expression in asymptomatic and mild pain patients compared to those with moderate to severe pain(>30mm on VAS). This exploratory study provides a molecular basis for the clinical diagnosis of pulpitis. With an enhanced understanding of pulpal inflammation, future studies on treatment and management of pulpitis and on pain associated with it can have a biological reference to bridge treatment strategies with pulpal biology.
No associated publication
Specimen part, Disease
View Samples