Identification of genes and pathways relevant to Cervical cancer pathogenesis. The study also aimed at identifying probable mechanistic differences in the low and high HOTAIR expressing cervical cancers patients .
Bridging Links between Long Noncoding RNA HOTAIR and HPV Oncoprotein E7 in Cervical Cancer Pathogenesis.
Age, Specimen part
View SamplesDownsream of GRID2 in the mouse cerebellum.
Altered Actions of Memantine and NMDA-Induced Currents in a New Grid2-Deleted Mouse Line.
Sex, Age
View SamplesPersistent Respiratory syncytial virus (RSV) infection in humans, animal models and cell lines have proven persistence of viral genomic RNA and mRNA for long periods of time. Cell lines are well-established models that can be used to study alterations in the expression profile of the host genome. We postulate that RSV persistence might also indirectly induce changes in the homeostasis of non-infected cells through soluble factors. Thus, we evaluated the effect of conditioned medium (CM) from MP cultures on the transcriptional profile of non-infected macrophages through gene expression microarrays
No associated publication
Specimen part, Cell line
View SamplesIntracellular progesterone receptor (PR) presents two main isoforms: PR-A and PR-B with different function and regulation. Both isoforms have been identified in astrocytomas, the most common and aggressive primary brain tumors in humans. To investigate the role of PR activity in the regulation of gene expression pattern of U373 cells, we evaluated by microarray analysis the profile of genes regulated by progesterone (10 nM), by a progesterone receptor antagonist (RU486, 10 M) or by both steroids.
No associated publication
Cell line
View Sampleswe performed genome-wide screening using SW480 cells with Gankyrin knockdown on an Affymetrix gene expression array to identify the transcriptional targets of Gankyrin
Gankyrin activates IL-8 to promote hepatic metastasis of colorectal cancer.
Specimen part, Cell line
View SamplesCharacterization of the Gallus gallus thrombocyte transcriptome under control and LPS stimulated conditions
No associated publication
Sex, Age, Specimen part, Cell line, Treatment
View SamplesTranscriptome analysis to compare parathyroid adenomas and normal parathyroid glands with the aim of identifying differentially expressed genes
No associated publication
Sex, Age, Specimen part, Disease, Race
View SamplesGenes encoding the circadian pacemaker in the hypothalamic suprachiasmatic nuclei (SCN) of mammals have recently been identified, but the molecubasis of circadian timing in peripheral tissue is not well understood. We used a bead-based microarray to identify mouse liver transcripts that show circadian cycles of abundance under constant conditions.
Comprehensive analysis of microRNA-mRNA co-expression in circadian rhythm.
Sex, Age, Specimen part
View SamplesThe type II transmembrane serine protease, TMPRSS2, which is expressed in the epithelia of the respiratory tract and can activate varieties of respiratory viruses. We have generated TMPRSS2 knockout (KO) mice. These mice showed normal development, growth, and fertility phenotypes, compared with wild-type mice.
No associated publication
No sample metadata fields
View SamplesKLF3, a member of the Krppel-like factor (KLF) family, is expressed in a wide range of cell types. It is involved in hematopoiesis of several blood cell lineages including erythrocyte and B lymphocyte. However, the research of regulatory roles on hematopoiesis of KLF3 in K562 cells has been still largely limited. To comprehensively assess the regulatory roles of KLF3 on hematopoiesis in K562 cells, a microarray analysis was performed in KLF3-deficient K562 cells. The differentially expressed genes were applied to IPA analysis to observe the perturbed hematopoiesis-associated functions, networks, and molecular pathways. This study will extensively assess the regulatory roles of KLF3 on hematopoiesis in K562 cells.
No associated publication
Cell line
View Samples