RNA-Seq analysis was performed to identify differentially expressed transcripts in primary AML bone marrow derived mononuclear cells compared to healthy (normal) peripheral blood mononuclear cells.
No associated publication
Sex, Age, Specimen part, Disease, Disease stage, Race
View SamplesWe have used lentiviral mediated knock down of SMARCB1, a subunit of the mammalian SWI/SNF complex in HL60, an acute promyelocytic leukemia cell line followed by high throughput mRNA sequencing to identify differentially expressed genes. We have used this data to identify genes affected by SMARCB1 depletion, and thus understand contribution of SMARCB1 towards leukemogenesis.
No associated publication
Sex, Age, Specimen part, Cell line
View SamplesWe investigate the molecular mechanisms of the RP9 mutation causing photoreceptor degeneration using the 661w cell
Targeted RP9 ablation and mutagenesis in mouse photoreceptor cells by CRISPR-Cas9.
Sex, Specimen part
View SamplesRP9 point mutation of 661w cell
Targeted RP9 ablation and mutagenesis in mouse photoreceptor cells by CRISPR-Cas9.
Sex, Specimen part
View SamplesRP9 konck out of 661w cell
Targeted RP9 ablation and mutagenesis in mouse photoreceptor cells by CRISPR-Cas9.
Sex, Specimen part
View SamplesThe goal of this study is to reveal the characters and therapeutic targets of CNS leukemia.
No associated publication
Sex, Age, Specimen part, Disease
View SamplesBuilding the gene expression profiles and identifying the differentially expressed genes in specific comparisons.
No associated publication
No sample metadata fields
View SamplesRNA-seq of single embryo
No associated publication
No sample metadata fields
View SamplesNIH-3T3 cells transduced with either EBF1-, PPARg2- or empty vector were stimulated with hormones to initiate adipocyte differentiation. RNA extraction was done using TriZol at d0, d2, d4 and d10 after stimulation. Samples were handled according to standard affymetrix protocols.
Gene expression analysis suggests that EBF-1 and PPARgamma2 induce adipogenesis of NIH-3T3 cells with similar efficiency and kinetics.
No sample metadata fields
View SamplesNPTX1 is a key inducer of neural lineages from the human ESC.
NPTX1 regulates neural lineage specification from human pluripotent stem cells.
Cell line, Time
View Samples