Examination of whole genome gene expression profiles from the placentas of cloned (somatic cell nuclear transfer, SCNT) and normally produced (control) calves using RNA-seq.The differentially expressed genes were analyzed between SCNT and control placentas.
No associated publication
Sex
View SamplesThis study goal is to obtain the different expression genes induced by APMAP knockdown.
No associated publication
Sex, Specimen part, Cell line
View SamplesThis study goal is to obtain the different expression genes induced by cholesterol.
No associated publication
Sex, Specimen part, Disease, Cell line
View SamplesNonresolving inflammation is correlated to carcinogenesis. Ulcerative colitis-associated colorectal cancer (UC-CRC), one of the typical carcinoma generated by inflammation that cannot be resolved properly, has been widely believed to involve a multistep process contains inflammation-dysplasia-cancer sequence. The exact molecular mechanisms underlying the step-wise development of UC-CRC is still not fully understood. Detecting the changes in gene expression profiles may help to reveal why and how does the prolonged inflammatory response lead to carcinogenesis, and to characterize potential diagnostic/prognostic markers or additional therapeutic targets for UC-CRC. There for, we performed temporal genome expression profiling analysis using the Affymetrix genome wide microarray system to identify broad scale changes in gene expression associated with the development of colitis-associated cancer, based on an AOM/DSS induced mouse model of UC-CRC.
Dynamic activation of the key pathways: linking colitis to colorectal cancer in a mouse model.
Disease, Disease stage
View SamplesDamage-associated molecular pattern (DAMP) molecules S100A8 and S100A9 with well-known functions in inflammation, tumor growth and metastasis. It has been found to have promote tumor cell proliferation activity at low concentration . However, the mechanism underlying this remains unclear. In the current study, we performed genome expression profiling analysis using the Affymetrix genome wide microarray system to identify broad scale changes in gene expression associated with S100a8 or S100a9 recombinant protein stimulation in murine colon carcinoma cell line CT26.WT.
Inflammation-induced S100A8 activates Id3 and promotes colorectal tumorigenesis.
Cell line
View SamplesTo investigated a detailed analysis of the transcriptional response between epithelial Caco-2 cells with different Bifidobacterium animals subsp. lactis KLDS 2.0603 cells ( Control and cells treated by digestive tract fluids simulated ).
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No sample metadata fields
View SamplesLaboratorial research
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Specimen part, Cell line
View Sampleshuman gene Transcriptome analysis
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Sex, Age, Specimen part
View SamplesSkeletal muscle is heterogeneous in nature and distinguished as red muscle and white muscle because of their myofiber composition. Soleus (SOL) is a typical red muscle and extensor digitorum longus (EDL) is a typical white muscle. In this study, we compared the transcriptome difference of soleus and extensor digitorum longus from three 10-week-old Yorkshire boars with porcine Affymetrix microarray.
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Sex, Age, Specimen part, Subject
View SamplesTranscriptome of connective tissue of swine affected and non-affected with scrotal hernia
No associated publication
Sex, Age, Specimen part, Disease
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