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accession-icon GSE71888
Transcriptional Profiles in Bursal B-Lymphoid DT40 Cells Infected with Very Virulent Infectious Bursal Disease Virus
  • organism-icon Gallus gallus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

Description

Infectious bursal disease virus (IBDV) causes a highly contagious, immunosuppressive disease in chickens. The virus mainly infects immature B lymphocytes in the bursa of Fabricius (BF). Chicken B cell line DT40, an avian leukosis virus-induced B cell line, supports very virulent IBDV (vvIBDV) infection in vitro and thereby serves as a good model for investigating the infection and pathogenesis of this virus. However, a transcriptome-wide understanding of the interaction between vvIBDV and B cells has not yet been achieved. This study aimed to employ time-course DNA microarrays to investigate gene expression patterns in DT40 cells after infection with vvIBDV strain LX.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Cell line, Time

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accession-icon SRP115993
Transcriptome sequence of RAW264.7 cell by Burkholderia pseudomallei infection
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Aims to find out differential expression genes (DEGs)in RAW264.7 cells during infection by Burkholderia pseudomallei infection

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line, Treatment

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accession-icon SRP125038
RNA sequencing of Ovaries from sheep with Double and Single Lamb
  • organism-icon Ovis aries
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

To screening for gene expression differences between the ovaries of Baimei mutton with double-lambs and single-lamb using RNA-Seq method

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part

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accession-icon GSE11025
Comparative transcriptional profiling of two contrasting rice genotypes in response to rice stripe virus infection
  • organism-icon Oryza sativa
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Rice Genome Array (rice)

Description

During the pathogenesis of virus disease, lots of changes occur in plant hosts including the altered gene expression profiles. Rice stripe virus (RSV) is the type member of Tenuivirus, transmitted by Laodelphax striatellus in a circulative propagative man

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP067368
Sus scrofa Transcriptome or Gene expression
  • organism-icon Sus scrofa
  • sample-icon 10 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

Sus scrofa has significant characteristics of high fecundity, roughage-resistance disease-resistance and cold-resistance,hence it is valuable to elucidate its transcriptome.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part

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accession-icon GSE71945
Expression data from porcine kidney cell (PK15) transfected by the plasmids
  • organism-icon Sus scrofa
  • sample-icon 59 Downloadable Samples
  • Technology Badge Icon Porcine Gene 1.1 ST Array (porgene11st)

Description

Several recombinat viruses of porcine circovirus type 2 (PCV2),including P1, P2, ZJ-R, VL258, and VL264, have been found. The PK15 cells were transfected by the molecular clones of the abovementioned viruses, where specific sets of genes are up-regulated or down-regulated.

Publication Title

Function analysis of proteins encoded by ORFs 1 to 8 of porcine circovirus-like virus P1 by microarray assay.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP150752
Gene Expression Profiling of the Early Pathogenesis of Wooden Breast Disease In Commercial Broiler Chickens Using RNA-Sequencing
  • organism-icon Gallus gallus
  • sample-icon 45 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

The main objective of this study was to decipher the gene expression profile associated with the onset and early development of Wooden Breast Disease in commercial broiler chickens. To achieve this, pectoralis major muscle biopsy samples were harvested from high-breast-muscle-yield, purebred broiler line. The pectoral biopsy samples were collected from the cranial (week 2 and 3) and caudal (week 4) aspects of the muscle belly in birds which were allowed to grow up to 7 weeks of age. Three subsets of biopsy samples comprising 6 unaffected (U) and 10 affected (A) from week 2 and 4 and 4U and 12A from week 3 were processed for RNA-sequencing analysis. All selected samples were processed using Truseq stranded mRNA LT sample kit for paired-end 2x75-nucleotide sequencing with Illumina Hiseq 2500 sequencer.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Disease

View Samples
accession-icon SRP082442
Transcriptome Analysis of post-hatch chicken hypothalamus under thermoneutral and heat stress conditions.
  • organism-icon Gallus gallus
  • sample-icon 33 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

No description.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Cell line, Treatment

View Samples
accession-icon GSE84417
Expression data from uterus tissue of sheep
  • organism-icon Ovis aries
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Ovine Gene 1.1 ST Array (ovigene11st)

Description

Embryo implantation is an essential step for the establishment of pregnancy and is crucial for the successful embryo transplantation of in vitro fertilization embryos. The successful implantation of an embryo depends upon cellular and molecular dialog between the uterus and the embryo.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE13203
Global transcriptional profiling of Staphylococcus aureus treated with cryptotanshinone
  • organism-icon Staphylococcus aureus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix S. aureus Genome Array (saureus)

Description

Staphylococcus aureus (S. aureus) is an important human and animal pathogen, multiply resistant strains are increasingly widespread, new agents are needed for the treatment of S. aureus. Cryptotanshinone, a natural plant product, has potent antimicrobial activity against S. aureus.

Publication Title

Genome-wide transcriptional profiling of the response of Staphylococcus aureus to cryptotanshinone.

Sample Metadata Fields

No sample metadata fields

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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