To identify factors and pathways regulated by IMP proteins and obtain leads to the mechanism behind the phenotypic changes, we compared the gene expression profiles of IMP siRNA treated cells with mock treated cells. Triplicate gene expression profiles were generated from both the IMP(1,3)A and IMP(1,3)B siRNA sets and were compared to the mock transfected cells. cRNA was hybridized to Affymetrix human U133A arrays.
RNA-binding IMPs promote cell adhesion and invadopodia formation.
Specimen part, Cell line
View SamplesCBX7-RIP-Seq data for HEK293T cells
No associated publication
Sex, Age, Specimen part, Cell line
View SamplesWe compared gene expression profiles between asymptomatic and symptomatic atherosclerotic plaques from the same patient. This was accomplished by analyzing carotid plaques from four patients with bilateral high-grade carotid artery stenoses one being symptomatic (TIA or stroke) and the other asymptomatic.
Microarray analysis reveals overexpression of CD163 and HO-1 in symptomatic carotid plaques.
Sex, Age, Specimen part, Disease, Disease stage, Subject, Time
View SamplesThis study was designed to identify root specific transcriptome variation that occurs across genotypically diverse maize lines.
No associated publication
Age, Specimen part, Disease
View SamplesThe purpose of this RNA-seq experiment was to perform a correlation analysis of mRNA expression levels in LPS-stimulated monocytes from patients with an IKZF1 mutant haploinsufficient phenotype (H167R-a and H167R-b are two siblings carrying IKZF1 p.H167R mutation) versus patients with an IKZF1 mutant dominant negative phenotype (C1, G1) along with five healthy normal controls (HC).
No associated publication
Sex, Specimen part
View SamplesGene expression profiling of normal hematopoietic cell subpopulations
Gene expression signatures in childhood acute leukemias are largely unique and distinct from those of normal tissues and other malignancies.
Specimen part
View SamplesThe purpose of this RNA-seq experiment was to perform a correlation analysis of mRNA expression levels in naïve CD4+ T cells from patients with an IKZF1 mutant haploinsufficient phenotype (H167R-a carries an IKZF1 p.H167R mutation) versus patients with an IKZF1 mutant dominant negative phenotype (C1, G1) along with five healthy normal controls (HC).
No associated publication
Sex, Specimen part
View SamplesAnalysis of gene expression in GL261 cells cultured adherently (AC) or as neurospheres (NS) using RNA-Seq
No associated publication
Sex, Specimen part, Cell line
View SamplesA transcriptomic approach to understand the physiological responses of peritoneal macropahges to estrogens
No associated publication
Sex, Age, Specimen part, Cell line, Treatment
View SamplesTranscriptome profiling of spleens from the triple peptide-immunized cohort showed substantial HD-specific differences including differential activation of genes associated with innate immune responses, absence of negative feedback control of gene expr
No associated publication
Specimen part
View Samples