Filters
Technology
Platform
Homo sapiens
48 Downloadable Samples
Illumina HiSeq 2500
Description
Gene expression for shNT, shTRRAP-a, and shTRRAP-b expressing cells at ALI day 4 and day 14 was measured using RNA sequencing technology. Each experimental condition was performed in duplicate with two independent donors. Cells expressing the shRNA constructs (RFP+) were sorted by FACS, and the RNA was isolated and prepared for next generation sequencing analysis.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Disease, Treatment
View Samples- Mus musculus
- 24 Downloadable Samples
- Illumina HiSeq 2500
Description
We performed unbiased high-throughput RNA sequencing (mRNA-seq) of total RNA samples isolated from Tsc1-deficient livers in Cre- or Cre+ mice.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Disease, Cell line, Treatment
View Samples- Mus musculus
- 8 Downloadable Samples
- Illumina HiSeq 2500
Description
To study gene expression in liver regeneration, we subjected control mice to DDC (1,4-dihydro-2,4,6-trimethyl-pyridine-3,5-dicarboxylate ) diet for 16 days, isolated EpCam+ CD31-/CD45-/Ter119- cells using fluorescence-activated cell sorting and used these cells for single cell transcriptome analysis.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Cell line, Treatment
View Samples- Mus musculus
- 185 Downloadable Samples
- Illumina HiSeq 2500
Description
To test the "one-neuron-one-receptor" rule of olfactory receptor expression, we sequenced the transcriptomes of single olfactory sensory neurons from the main olfactory epithelium of adult (1 to 3 months) and newborn mice (postnatal day 4 to 10).
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples- Homo sapiens
- 8 Downloadable Samples
Illumina HumanHT-12 V4.0 expression beadchip
Description
In the present study, we have characterized the putative Cancer Stem Cell population of Oral Squamous Cell Carcinoma by various cellular and molecular assay. Subsequently we performed gene expression profiling of SCC25 cell line with CD44highCD24low(CSC) and CD44lowCD24high(Non-CSC) phenotypes using illumina BeadChip Array. Further, systematic computational analysis was performed to identify CSC-like gene signatures in the oral cancer cells. Differentially expressed genes were subjected to pathway analysis in IPA. The analysis lead to the identification of few relevant signaling pathway implicated in stemness.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples- Homo sapiens
- 6 Downloadable Samples
- Illumina HumanHT-12 V4.0 expression beadchip
Description
Colorectal cancer cells with TP53 mutation are highly resistant to chemotherapeutics. In order to identify potential chemo-resistance signatures, here; we explored the global gene expression profiles of drug resistant colorectal cancer cell line SW480 upon Floxuridine (FdUrd) treatment using Illumina Human HT-12 v4.0 Expression Beadchip Array. Further, significantly altered genes were subjected to the pathway analysis in GeneCodis3 and crucial signaling pathways were found to be enriched. Upon further functional validations, these pathways could be targeted to enhance therapy in human cancers harboring mutant p53.
Publication Title
Transcriptome profiling identifies genes and pathways deregulated upon floxuridine treatment in colorectal cancer cells harboring GOF mutant p53.
Sample Metadata Fields
Sex, Age, Specimen part, Cell line, Treatment
View Samples
SRP138008- Homo sapiens
- 4 Downloadable Samples
- Illumina HiSeq 4000
Description
This study was performed to investigate the effect of IL-37 on the transcriptional profile of eosinophils upon co-culture with human bronchial epithelial BEAS-2B cells and peptidoglycan (PGN) stimulation.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Disease, Treatment
View Samples- Arabidopsis thaliana
- 4 Downloadable Samples
- Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)
Description
GSH, being a versatile molecule, is actively involved in various bilogical processe of plant system. Our previous studies identifies an active role of GSH in plant defense signaling network. Here, we used microarray under GSH treated condition to obtain a global expression profiling under this altered GSH conditions.
Publication Title
No associated publication
Sample Metadata Fields
Age, Specimen part
View Samples- Homo sapiens
- 4 Downloadable Samples
- Affymetrix Human Gene 2.0 ST Array (hugene20st)
Description
Preclinical cancer drug discovery efforts have employed two-dimensional (2D)-cell-based assay models, which fail to forecast in vivo efficacy and contribute to a lower success rates of clinical approval. Three-dimensional (3D) cell culture models are recently expected to bridge the gap between 2D and in vivo models. We have developed novel 3D culture method that improves the growth of spheroid-forming cancer cells under anchorage-independent condition by leveraging a feature of FP001.
Publication Title
No associated publication
Sample Metadata Fields
Cell line
View Samples- Homo sapiens
- 2 Downloadable Samples
- Affymetrix Human Gene 2.0 ST Array (hugene20st)
Description
Preclinical cancer drug discovery efforts have employed two-dimensional (2D)-cell-based assay models, which fail to forecast in vivo efficacy and contribute to a lower success rates of clinical approval. Three-dimensional (3D) cell culture models are recently expected to bridge the gap between 2D and in vivo models. We have developed a novel 3D culture method that improves the growth of spheroid-forming cancer cells under anchorage-independent condition by leveraging a feature of FP001, a bacteria-derived polysaccharide.
Publication Title
No associated publication
Sample Metadata Fields
Cell line, Treatment
View Samples