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accession-icon GSE56352
Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer
  • organism-icon Homo sapiens
  • sample-icon 21 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

We analyzed transcriptional changes in 4 prostate cancer cell lines following treatment with the BET inhibitor I-BET762 using Affymetrix Human Genome U133 Plus 2.0 Arrays.

Publication Title

Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer.

Sample Metadata Fields

Cell line, Time

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accession-icon GSE112282
Gene expression changes induced by the BET inhibitor GSK525762 and/or the MEK inhibitor trametinib in cancer cell lines.
  • organism-icon Homo sapiens
  • sample-icon 45 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Transcriptional changes were analyzed in two colorectal cancer, two pancreatic cancer, and one small cell lung cancer cell line following treatment with the BET inhibitor GSK525762 and/or the MEK inhibitor trametinib using Affymetrix Human Genome U133 Plus 2.0 Arrays.

Publication Title

MEK inhibitors overcome resistance to BET inhibition across a number of solid and hematologic cancers.

Sample Metadata Fields

Cell line, Treatment, Time

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