Response of JHCO9 and JHOC5 cells to infection with NT (control) lentivirus or one of two knockdown lentiviruses, SPINK1 KD or IL-6 KD.
Targeting an autocrine IL-6-SPINK1 signaling axis to suppress metastatic spread in ovarian clear cell carcinoma.
Specimen part, Cell line
View SamplesResponse of pancreas cancer cells to treatment with recombinant MMP3
Tumor cell-derived MMP3 orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma.
Specimen part, Cell line, Treatment
View SamplesResponse of mouse mammary epithelial cells to treatment with MMP3
ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-kB-dependent activation of Snail.
Specimen part, Treatment
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.
Specimen part, Cell line
View SamplesResponse of mouse mammary epithelial cells to different cell densities and treatment with MMP3
Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.
Specimen part, Cell line
View SamplesResponse of mammary epithelial cells to different cell densities
Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.
Specimen part, Cell line
View SamplesTo determine how aging impacts gene expression in hematopoietic stem cells (HSCs), human CD34+ cells from bone marrow (34BM) and mobilized stem cell products (34P38NPBSC) were examined using microarray-based expression profiling. Differential expression changes were confirmed by microarray comparisons of younger and older expanded T-cell populations.
Decreased IRF8 expression found in aging hematopoietic progenitor/stem cells.
No sample metadata fields
View SamplesWe used microarrays to analyze the gene expression profile of CD34+CD45RA+CD7+, CD34+CD45RA+CD10+CD19- and CD34+CD45+CD7-CD10-CD19- HPCs isolated from umbilical cord blood
Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood.
Specimen part
View SamplesExpression profiles of acute myeloid leukemia patient samples.
Identification of genes with abnormal expression changes in acute myeloid leukemia.
No sample metadata fields
View SamplesAcute myeloid leukemia (AML) is one of the most common and deadly forms of hematopoietic malignancies. We hypothesized that microarray studies could identify previously unrecognized expression changes that only occur only in AML blasts. We were particularly interested in those genes with increased expression in AML, believing that these genes may be potential therapeutic targets.
Identification of genes with abnormal expression changes in acute myeloid leukemia.
Sex, Disease
View Samples