We explored the functional role of YAP in SCLC cells (SBC3 and SBC5) by YAP knockdown.
YAP and TAZ modulate cell phenotype in a subset of small cell lung cancer.
Cell line
View SamplesCutaneous exposure to food antigen through impaired skin barrier has been shown to induce epicutaneous sensitization, and thereby cause IgE-mediated food allergy.
Skin inflammation exacerbates food allergy symptoms in epicutaneously sensitized mice.
Sex, Specimen part
View SamplesAnalysis to find splicing variants that are differentially expressed in a highly metastatic stomach cancer cell line, MKN45P, versus its parental cell line, MKN45
Identification of a novel protein isoform derived from cancer-related splicing variants using combined analysis of transcriptome and proteome.
Specimen part, Cell line
View SamplesTo identify gene expression profiles in those periodontitis-associated fibroblasts (PAFs) versus normal gingival fibroblasts to determine their molecular repertoire, and exploit it for therapeutic intervention.
Fibroblast VEGF-receptor 1 expression as molecular target in periodontitis.
Specimen part, Subject
View SamplesTranscriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis
Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis.
Specimen part
View SamplesTranscriptome analyses of normal gingival fibroblasts after knockdown of DLX5 and RUNX2 long forms.
Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis.
Specimen part
View SamplesTo investigate the roles of TAZ in lung cancer cell proliferation, we compared the expression profiles of A549 and H441 lung adenocarcinoma cell lines transfected with control siRNA and siTAZ.
An integrative analysis of the tumorigenic role of TAZ in human non-small cell lung cancer.
Specimen part, Cell line
View SamplesTBX4 is a transcription factor unique to lung fibroblasts and is associated with super-enhancer. RNA-sequencing analysis on NHLFs following TBX4 knockdown revealed a broad array of genes possibly regulated by TBX4. Overall design: NHLFs were transfected with siRNAs for TBX4, and RNA-sequencing was performed using Illumina HiSeq.
TBX4 is involved in the super-enhancer-driven transcriptional programs underlying features specific to lung fibroblasts.
Subject
View SamplesRNA-seq of normal gingival fibroblasts Overall design: RNA-seq of normal gingival fibroblasts
Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis.
Specimen part, Subject
View SamplesTo investigate the roles of MYEOV in lung cancer cell proliferation, we compared the expression profiles of A549 lung adenocarcinoma cell lines transfected with control siRNA and siMYEOV.
Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC.
Cell line
View Samples