The double-stranded RNA binding protein Staufen2 (Stau2) is asymmetrically localized and segregated during asymmetric cell divisions in the developing mouse cortex and promotes intermediate progenitor cell fate.
Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes lineage progression.
Specimen part
View Samples10 day old seedlings were treated with 5uM of the cytokinin Benzyladenine(BA)or DMSO at 15min, 45min, 120min, 480min and 1440min
Expression profiling of cytokinin action in Arabidopsis.
Age, Compound, Time
View SamplesCellcell communication is critical for tissue and organ development. In plants, secretory CLAVATA3/EMBRYO SURROUNDING REGION-related (CLE) peptides function as intercellular signaling molecules in various aspects of tissue development. However, little is known about intracellular signaling pathways functioning in vascular development downstream of the CLE ligands. To elucidate CLE signaling pathway, we performed GeneChip analysis.
CLE peptides can negatively regulate protoxylem vessel formation via cytokinin signaling.
Specimen part
View SamplesInducible overexpression of Arabidopsis meristem regulators by AlcR / AlcA system. Plants harboring 35S::AlcR/AlcA::GOI (GUS control, LEAFY, SHOOTMERSTEMLESS, WUSCHEL)constructs were grown in continous light for 12 days and induced with 1% Ethanol. After 12h of EtOH treatment, seedlings were dissected and RNA was processed from the shoot apex and young leaves. Affymetrix Ath1 arrays were hybridized in duplicates from each experiment.
WUSCHEL controls meristem function by direct regulation of cytokinin-inducible response regulators.
Age, Specimen part, Subject, Compound
View SamplesAim of this experiment was to look at the gene expression differences in the benzyladenine-treated and untreated Arabidopsis seedlings grown in light
Identification of cytokinin-responsive genes using microarray meta-analysis and RNA-Seq in Arabidopsis.
Age, Specimen part, Compound
View SamplesAim was to look at the gene profile changes in 10 days old Arabidopsis seedlings grown in light and treated with either Zeatin or BA and compared to non-treatment
Identification of cytokinin-responsive genes using microarray meta-analysis and RNA-Seq in Arabidopsis.
Age, Compound
View SamplesWe find that sub-set of cytokin repsonse genes are not regulated at WT levels in the bpc1,2,3,4,6 mutant. Overall design: Whole ten-day-old seedlings of WT and the bpc1,2,3,4,6 mutant were treated with synthetic cytokinin (benzyladenine) or a vehicle control (NaOH) for 1 hour and root tissue was isolated.
Role of BASIC PENTACYSTEINE transcription factors in a subset of cytokinin signaling responses.
Specimen part, Treatment, Subject
View SamplesEffect of the cytokinin BA on wt and arr1,10,12 mutant seedlings
Type B response regulators of Arabidopsis play key roles in cytokinin signaling and plant development.
Age, Specimen part
View SamplesGene expression profile of cancer cell lines of breast, lung, pancreatic, gasctric, ovarian, hepatocellular, prostate carcinomas and melanomas.
Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations.
No sample metadata fields
View SamplesIn order to understand differentially regulated gene expression after the different treatments, 4 size matched tumors of each group were analyzed by microarrays.
Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade.
Specimen part
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