The bone marrow microenvironment in Large Granular Lymphocyte Leukemia (LGLL) patients has been unexplored for its role in the development of cytopenias, which lead to complications resulting in the most prominent causes of morbidity and mortality.
Fibrosis and subsequent cytopenias are associated with basic fibroblast growth factor-deficient pluripotent mesenchymal stromal cells in large granular lymphocyte leukemia.
Specimen part, Disease, Disease stage
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