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refine.bio helps you build ready-to-use datasets with normalized transcriptome data from all of the world’s genetic databases.
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accession-icon GSE93987
Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder
  • organism-icon Homo sapiens
  • sample-icon 207 Downloadable Samples
  • Technology Badge Icon Affymetrix HT HG-U133+ PM Array Plate (hthgu133pluspm)

Description

Schizophrenia is associated with alterations in working memory that reflect dysfunction of dorsolateral prefrontal cortex (DLPFC) circuitry. Working memory depends on the activity of excitatory pyramidal cells in DLPFC layer 3, and to a lesser extent in layer 5.

Publication Title

Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE29565
Expression data from chicken embryonic fibroblasts infected with Toxoplasma gondii
  • organism-icon Gallus gallus
  • sample-icon 31 Downloadable Samples
  • Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.

Sample Metadata Fields

Cell line, Time

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accession-icon GSE29563
Host responses in chicken embryonic fibroblasts infected with different strains of Toxoplasma gondii [F1 progeny]
  • organism-icon Gallus gallus
  • sample-icon 21 Downloadable Samples
  • Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

Description

Toxoplasma gondii is a ubiquitous protozoan pathogen able to infect both mammalian and avian hosts. Surprisingly, just three strains appear to account for the majority of isolates from Europe and N. America.

Publication Title

Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.

Sample Metadata Fields

Cell line, Time

View Samples
accession-icon GSE29562
Strain-dependent host responses in chicken embryonic fibroblasts infected with Toxoplasma gondii [ME49, CEP, and Mock]
  • organism-icon Gallus gallus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

Description

Toxoplasma gondii is a ubiquitous protozoan pathogen able to infect both mammalian and avian hosts. Surprisingly, just three strains appear to account for the majority of isolates from Europe and N. America.

Publication Title

Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.

Sample Metadata Fields

Cell line, Time

View Samples
accession-icon GSE55298
Toxoplasma RH and Mock Infection of macrophages
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Infection of RAW264.7 cells with RHku80 parasites or mock-infection for 24 hours

Publication Title

Infection by Toxoplasma gondii specifically induces host c-Myc and the genes this pivotal transcription factor regulates.

Sample Metadata Fields

Cell line

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accession-icon GSE29564
ROP16-dependent host transcriptional responses in chicken embryonic fibroblasts infected with T. gondii [RH, ROP16-KO]
  • organism-icon Gallus gallus
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

Description

Toxoplasma gondii is a ubiquitous protozoan pathogen able to infect both mammalian and avian hosts. Surprisingly, just three strains appear to account for the majority of isolates from Europe and N. America.

Publication Title

Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.

Sample Metadata Fields

Cell line, Time

View Samples
accession-icon E-MEXP-958
Transcription profiling of human wild type and deltaTOR-containing hepatocyte-like cells to compare total RNA and polysome-bound RNA populations upon hepatocytic differentiation
  • organism-icon Homo sapiens
  • sample-icon 22 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

Comparison of Total RNA and Polysome-bound RNA populations in deltaTOR containing cells and control cells upon hepatocyitc differentiation.

Publication Title

Mammalian target of rapamycin activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growth.

Sample Metadata Fields

Specimen part, Cell line

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accession-icon GSE3842
LD/DD time course of y w; tim01, cn bw, and y w Drosophila
  • organism-icon Drosophila melanogaster
  • sample-icon 70 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome Array (drosgenome1)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Control of daily transcript oscillations in Drosophila by light and the circadian clock.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE6542
Circadian time course
  • organism-icon Drosophila melanogaster
  • sample-icon 46 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome Array (drosgenome1)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Integration of light and temperature in the regulation of circadian gene expression in Drosophila.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE56534
Infection of macrophages by Toxoplasma Progeny from a Type II x Type III cross
  • organism-icon Mus musculus
  • sample-icon 32 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Infection of RAW264.7 cells for 24 hours with 32 Toxoplasma Progeny from a Type II x Type III cross

Publication Title

GRA25 is a novel virulence factor of Toxoplasma gondii and influences the host immune response.

Sample Metadata Fields

No sample metadata fields

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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