VD3-VDR axis regulates the homeostasis and function of alveolar macrophage [RNA-Seq]

Purpose: To understand the regulation of gene expression of alveolar macrophages by VD3-VDR axis Overall design: Fresh isolated WT alveolar macropahges (AM) were treated with or without 50 nM Vitamin D3 in vitro for 24hrs. Fresh AMs were isolated from WT and VDR knockout mice in 4 and 10 weeks old. RNA was isolated and purified by Qiagen Rneasy micro kit and applied to RNAseq.

12

Hu G, Dong T, Wang S, Jing H, Chen J