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Accession IconSRP173593

Single cell RNA-seq of 25 thousand epithelial cells from xenografts of triple-negative breast cancers

Organism Icon Homo sapiens
Sample Icon 2 Downloadable Samples
Technology Badge IconNextSeq 500

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Description
Patient derived xenografts (PDX) were created from two triple-negative breast cancers (PDX-110 and PDX-332) taken at the time of surgery from drug-naive patients. Freshly sorted epithelial cells were profiled by single-cell RNA-seq (scRNA-seq) using a 10X Genomics Chromium System. Overall design: Transcriptional profiling was completed for 10,060 total epithelial cells from PDX-110 and 14,681 total epithelial cells from PDX-322.
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