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Accession IconSRP171933

Bulk RNA-Seq profiling of progenitor exhausted (Slamf6+Tim-3-) and terminally exhausted (Slamf6-Tim-3+) CD8+ T-cells from tumors and chronic viral infection

Organism Icon Mus musculus
Sample Icon 54 Downloadable Samples
Technology Badge IconNextSeq 500

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Description
Transcriptionally similar subpopulations of exhausted CD8+ T-cells are found in chronic viral infection and tumors Overall design: RNA-seq analysis of progenitor exhausted and terminally exhausted CD8+ T-cells isolated from spleens of mice chronically infected with LCMV Clone 13 (day 30 post-infection) or isolated from B16-ova tumors (day 22 post tumor implantation), with or without anti-PD-1 treatment
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54
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