Integrative analysis of single cell genomics data by coupled nonnegative matrix factorizations (RNA-Seq)

464 scRNA-seq samples generated for the retinoic acid-induced mESC differenation at day 4. Overall design: We present a method(Coupled NMF) to cluster single cell chromatin accessibility data and single cell gene expression data simultaneously.

464

Zeng W, Chen X, Duren Z, Wang Y, Jiang R, Wong WH