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Accession IconSRP150074

Transcriptome landscape of human primary monocytes response upon different ligand glucocorticoids

Organism Icon Homo sapiens
Sample Icon 8 Downloadable Samples
Technology Badge IconNextSeq 500

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Description
Glucocorticoids (GCs) are essential steroid hormones that regulate the immune system. GCs have been widely used to treat various inflammation disorders and auto-immune diseases, due to their potent immune repression properties. Overall design: Monocytes from healthy donors were cultured in the presence of 100 nM triamcinolone acetonide (TA), 100 nM Dexamethasone (Dex) or 100 nM Prednisolone (Pred) for 4 hours. Cells were then collected for RNA-seq.
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8
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