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Accession IconSRP149965

Understanding the role of PCAT92 in prostate cancer

Organism Icon Homo sapiens
Sample Icon 6 Downloadable Samples
Technology Badge IconIllumina HiSeq 2500

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Description
Many lncRNA are known to be differential expressed in prostate cancer. One such lncRNA is PCAT92, which by has been shown to be over-expressed in prostate cancer samples when compared to adjacent normal tissue. PCAT92 shares its chromosomal locus with ABCC4, a genes already reported to be implicated in prostate cancer. Here we have explored the possible mechanism by which PCAT92 is playing a role in prostate cancer. Here we made LNCaP which were knockdown PCAT92 and ABCC4 independently and performed a RNA-sequencing to see the change in gene expression under both the knockdown condition.
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