github link
Accession IconSRP141364

Genome-wide transcriptional analysis of human patterned induced neurons (hpiNs)

Organism Icon Homo sapiens
Sample Icon 412 Downloadable Samples
Technology Badge IconNextSeq 500, Illumina HiSeq 2500

Submitter Supplied Information

Description
We report that combining NGN2 programming with SMAD and WNT inhibition generates patterned induced neurons (hpiNs).Transcriptional analyses showed that hpiN cultures contained cells along a developmental continuumranging from poorly differentiated neuronal progenitors to well-differentiated, excitatory glutamatergic neurons. The most differentiated neurons could be identified using a CAMK2A::GFP reporter gene. Overall design: RNA sequencing analysis (population and single cell) over hpiNs differentiation time (D0 through D49 after induction). Two independent iPS lines, 9 time points, three replicates each.
PubMed ID
Total Samples
413
Submitter’s Institution
No associated institution

Samples

Show of 0 Total Samples
Filter
Add/Remove
Accession Code
Title
Specimen part
Disease
Cell line
Subject
Time
Processing Information
Additional Metadata
No rows found
Loading...