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Accession IconSRP135797

Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer [ 10x genomics]

Organism Icon Homo sapiens
Sample Icon 29 Downloadable Samples
Technology Badge IconIllumina HiSeq 2500

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Description
High numbers of tissue-resident memory T (TRM) cells have been associated with better clinical outcomes in cancer patients. However, the molecular characteristics that drive their efficient immune response to tumors are poorly understood. Here, using single-cell and bulk transcriptomic analysis of purified populations of TRM and non-TRM cells we characterise these populations Overall design: Population and single cell profiling of subtypes of CD8 cells isolated from human lung and lung tumour samples with flow cytometry
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30
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No associated institution

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