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Accession IconSRP132239

Transcriptomic analysis of multiple myeloma cell lines

Organism Icon Homo sapiens
Sample Icon 13 Downloadable Samples
Technology Badge IconIon Torrent Proton

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Description
We found that a small molecule inhibitor of PRMT4 inhibited cell growth of a subset of multiple myeloma cell lines. To identify biomarkers that predict the sensitivity of myeloma cells to PRMT4 inhibition, we performed transcriptomic analysis of multiple myeloma cell lines. Overall design: Amplicon sequencing of thirteen multiple myeloma cell lines was performed on the Ion Torrent platform. Steady-state gene expression profile of sensitive cells were compaired with that of insensitive cells.
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13
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