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Accession IconSRP127547

mRNA sequencing to assess RfxCasR and matching shRNA specificity

Organism Icon Homo sapiens
Sample Icon 21 Downloadable Samples
Technology Badge IconNextSeq 500

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Description
Matching sets of RfxCasR and shRNAs targeting ANXA4 and B4GALNT1 plus non-targeting (NT) controls were profiled by mRNA sequencing to compare non-specific transcriptome perturbations for both shRNA and RfxCasR technologies. Overall design: Three biological replicates for 3 shRNAs and 2 RfxCasR guide RNAs plus 2 RfxCasR arrays expresssed in HEK 293FT cells
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21
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No associated institution

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