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Accession IconSRP126999

Beta-catenin maintains lung epithelial progenitors after lung specification

Organism Icon Homo sapiens
Sample Icon 4 Downloadable Samples
Technology Badge IconNextSeq 500

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Description
We performed RNA-seq on human embryonic stem cells raised in an established condition to produce 95% Nkx2.1 cells, with and without withdrawal of Wnt-agonist CHIR99021 or addition of Wnt-inhibitor IWP2 Overall design: Human lung progenitors were derived from RUES2 as described in Huang et al 2014, Huang et al 2015. Wnt agonist withdrawal or addition of Wnt inhibitor was done at day 12, with cell harvest for RNA-seq at day 12 (control) and day 15 (control and treatment)
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4
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