Regulation and function of H3K36 di-methylation by the trithorax-group protein complex AMC

The goal of this study was to identify genes that are differentially expressed in animals that lack the histone methyltransferase Ash1 that generates H3K36 di-methylation Overall design: Comparison of the transcriptome in 3rd leg and haltere imaginal discs (T3 discs) and in wing imaginal discs (T2 discs) between wild-type animals and in animals that were homozgyous for the ash1[22] null mutation

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Schmähling S, Meiler A, Lee Y, Mohammed A, Finkl K, Tauscher K, Israel L, Wirth M, Philippou-Massier J, Blum H, Habermann B, Imhof A, Song JJ, Müller J