Bmp2 and Notch cooperate to pattern the embryonic endocardium

Our study describes in detail the role of Bmp2 during cardiac valve developmnent and its implication in Notch pathway activation. Overall design: Hearts were isolated from WT and Bmp2GOF;Nkx2.5-Cre mouse embryos at stage E9.5 and their expression profile characterized by RNA-seq

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Papoutsi T, Luna-Zurita L, Prados B, Zaffran S, de la Pompa JL