Zebrafish Rfx4 controls dorsal and ventral midline formation in the neural tube

RNA-seq transcriptome analysis identified a functional requirement for zebrafish Rfx4 in the developing neural floor plate and roof plate. Overall design: Embryos derived from an rfx4uw8013/+ incross were sorted by phenotype into mutant and sibling groups. RNA was prepared from each individual embryo at ~ 25 hpf

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Sedykh I, Keller AN, Yoon B, Roberson L, Moskvin OV, Grinblat Y