Transcriptional responses induced by controlled human malaria infection (CHMI)

SRP102683

Homo sapiens

39 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

Whole blood RNA-Seq was applied to investigate gene expression kinetics in Tanzanian males who underwent controlled malaria infection by intradermal injection with aseptic, purified, cryopreserved Plasmodium falciparum sporozoites. Overall design: 10 volunteers injected intradermally with a total of 25'000 infectious Plasmodium falciparum sporozoites (PfSPZ).

PubMed ID

29920562

Publication Title

Whole blood transcriptome changes following controlled human malaria infection in malaria pre-exposed volunteers correlate with parasite prepatent period.

Total Samples

Submitter’s Institution

No associated institution

Authors

Rothen J, Murie C, Carnes J, Anupama A, Abdulla S, Chemba M, Mpina M, Tanner M, Lee Sim BK, Hoffman SL, Gottardo R, Daubenberger C, Stuart K

Source Repository

Sequence Read Archive (SRA)

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