github link
Accession IconSRP081444

Catch-and-release of cytokines converts transient exposure into long-term inflammatory responses

Organism Icon Mus musculus
Sample Icon 14 Downloadable Samples
Technology Badge IconIllumina HiSeq 2000

Submitter Supplied Information

Description
We report that after cancer cells are exposed to a transient pulse (5h) of the pro-inflammatory cytokine IFN?, they continue up-regulating genes in the antigen presentation pathway for days after abrogation of the original signal. We discovered that a new mechanism of cell-to-cell communication, cytokine catch-and-release, explains this surprising result. Overall design: Examination of IFN?-induced gene expression over multiple timepoints in mouse melanoma cells
PubMed ID
Total Samples
14
Submitter’s Institution
No associated institution

Samples

Show of 0 Total Samples
Filter
Add/Remove
Accession Code
Title
Specimen part
Cell line
Subject
Processing Information
Additional Metadata
No rows found
Loading...