Integrative analysis of DNA methylation and expression during EPC differentiation_mRNA-Seq

Analysis of DNA methylation and gene expression changes during regulated endothelial progenitor cells (EPCs) to outgrowth endothelial cells (OECs). Results provide information of DNA methylation and gene expression pattern during cord-blood derived EPCs differentiation. Taken together, we discovered specific set of genes regulated by hyper- and hypo-methylation during differentiation. Overall design: mRNA and MeDIP seq using total RNA and genomic DNA isolated from cord blood-derived EPCs and OECs.

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Jeong Y, Jun Y, Kim J, Park H, Choi KS, Zhang H, Park JA, Kwon JY, Kim YM, Lee S, Kwon YG