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Accession IconSRP077574

Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade [RNA-Seq]

Organism Icon Mus musculus
Sample Icon 29 Downloadable Samples
Technology Badge IconIllumina HiSeq 2000

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Description
The goal of this study is to investigate if interferon signaling regulates immune checkpoint blockade in mouse melanoma model. Overall design: Transcription profiling for B16, B16 after chronic interferon treatment, B16 derived checkpoint blockade resistant strain 499 and various knockout from 499, coupled with ATA-seq data.
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29
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No associated institution

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