Benomyl toxicity links histone H3 lysine 4 methylation to cell cycle control

The PAT-seq approach was utilised to determine the gene expression changes over the cell-cycle of wildtype and delta-set1 yeast strains. The cell were synchronised by alpha-factor arrest and cell-cycle release Overall design: Analysis gene expresson across the S. cerevisiae cell cycle.

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Beilharz TH, Harrison PF, Miles DM, See MM, Le UM, Kalanon M, Curtis MJ, Hasan Q, Saksouk J, Margaritis T, Holstege F, Geli V, Dichtl B