Tet-mediated DNA hydroxymethylation regulates retinal neurogenesis in zebrafish via cell-extrinsic signaling pathways

SRP073099

Danio rerio

24 Downloadable Samples

Illumina HiSeq 2500, NextSeq 500

Submitter Supplied Information

Description

Using zebrafish tet2-/-;tet3-/- mutants, we identify functions for Tet enzymes and 5-hydroxymethylcytosine (5hmC) in regulating gene expression and cell type-specific differentiation during retinal development. Overall design: RNAseq from tet2-/-;tet3-/- mutant and sibling embryonic eye tissues dissected at 72hpf and 36hpf.

PubMed ID

28926578

Publication Title

Tet-mediated DNA hydroxymethylation regulates retinal neurogenesis by modulating cell-extrinsic signaling pathways.

Total Samples

Submitter’s Institution

No associated institution

Authors

Seritrakul P, Gross JM

Source Repository

Sequence Read Archive (SRA)

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