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Accession IconSRP066177

Differential expression of RNAs in E9 tuft rostrums with NTDs

Organism Icon Mus musculus
Sample Icon 3 Downloadable Samples
Technology Badge IconIon Torrent Proton

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Purpose: Identify genes and pathways affected in tuft embryos with NTDs Results: Expression of genes associated with neural tube closure and components of non-canonical WNT signaling/PCP pathways were affected Conclusions: TET1 regulates genes associated with neural tube closure Overall design: RNA pooled from the rostrums of E9 (18-22 somites) tuft/tuft embryos with NTD compared with respective wildtype background strain
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3
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