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Accession IconSRP061381

Splenic bridging channel dendritic cells survey red blood cells for missing self-CD47

Organism Icon Mus musculus
Sample Icon 4 Downloadable Samples
Technology Badge IconIllumina HiSeq 2500

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Description
In vivo exposure of  mouse CD4+ splenic DCs to sheep red blood cells causes prompt induction of multiple genes associated with DC activation. Overall design: mRNA profiles from CD4 dendritic cells (sorted from mice immunized with either sheep red blood cells or PBS) were generated using an Illumia HiSeq 2500. Sequence reads passing a quality filter were aligned to mouse genome (mm10) using Tophat.
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4
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