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Accession IconSRP060744

Single-cell RNA sequencing of aspirates from cortical neurons after patch clamp recording

Organism Icon Mus musculus
Sample Icon 83 Downloadable Samples
Technology Badge IconIllumina HiSeq 2000

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Description
We obtained full transcriptome data from single cortical neurons after whole-cell patch-clamp recording (termed “Patch-seq”). By applying “Patch-seq” to cortical neurons, we reveal a close link between biophysical membrane properties and genes coding for neurotransmitter receptors and channels, including well-established and hitherto undescribed subtypes. Overall design: RNA sequencing was performed on a total of 83 individual cells
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83
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