Endogenous DAF-16 genome-wide recruitment under low Insulin signalling condition in Caenorhabditis elegans

In order to understand the complexity of gene regulation downstream of IIS, we did RNA-seq in mixed culture in wild-type, daf-2(e1370), daf-16(mgDf50);daf-2(e1370) and daf-2(e1370);daf-12(m20 and correlated it with ChIP-seq data Overall design: RNA-seq profile of different mutants in mix stage

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Kumar N, Jain V, Singh A, Jagtap U, Verma S, Mukhopadhyay A