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Accession IconSRP050179

RNA-seq of human fibroblasts during replicative senescence

Organism Icon Homo sapiens
Sample Icon 45 Downloadable Samples
Technology Badge IconIllumina HiSeq 2000

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Description
Senescent human fibroblasts were compared to young proliferating fibroblasts. Five different cell lines were compared. Illumina sequencing (HiSeq2000) was applied to generate 50bp single-end reads. Jena Centre for Systems Biology of Ageing - JenAge (www.jenage.de) Overall design: 48 samples: 3 biological replicates for each group: young proliferating and senescent BJ cells; young proliferating and senescent Wi-38 cells; young proliferating and senescent IMR-90 cells; 5 population doubling from young proliferating to senescent cell for HFF and MRC-5 cells
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45
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No associated institution

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