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Accession IconSRP041516

Mouse ESC Transcriptome or Gene expression

Organism Icon Mus musculus
Sample Icon 8 Downloadable Samples
Technology Badge IconIllumina HiSeq 2500

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Description
PRMT5 is a type II protein arginine methyltransferase (PRMT) with roles in cancer, reprogramming and neurogenesis. In pluripotent stem cells PRMT5 prevents naïve stem cell differentiation however its role in ground state pluripotency is unknown. Our goal of this study is to demonstrate the essential role of PRMT5 in ground state pluripotency and PGC development.
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