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Accession IconSRP019915

Gene expression analysis of murine peritoneal macrophages deficient for SAMHD1 and IFNAR

Organism Icon Mus musculus
Sample Icon 22 Downloadable Samples
Technology Badge IconIllumina HiSeq 2000

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Description
To investigate the contribution of type-1 IFN signalling to the upregulation of IFN- stimulated genes in SAMHD1-deficient cells, we performed global gene expression analysis of SAMHD1-deficient IFNAR-/- macrophages. Overall design: Peritoneal macrophages from ten SAMHD1-deficient IFNAR-/- and six SAMHD1-deficient controls were FACS sorted. RNA was subjected to next generation mRNA sequencing.
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26
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