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Accession IconSRP013761

Fcp1 dephosphorylation of the RNA polymerase II C-terminal domain required for efficient transcription of heat shock genes

Organism Icon Drosophila melanogaster
Sample Icon 4 Downloadable Samples
Technology Badge IconIllumina Genome Analyzer

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Description
RNA polymerase II is decreased on heat shock-induced genes when the CTD phosphatase Fcp1 is knocked down in Drosophila S2 cells. We examined transcriptionally-engaged Pol II genome-wide with GRO-seq to determine if other genes are similarly affected. Overall design: Two biological replicates of nascent RNA sequencing
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