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Accession IconGSE9644

Glucose Pulse to sfp1delta continuous cultures

Organism Icon Saccharomyces cerevisiae
Sample Icon 26 Downloadable Samples
Technology Badge Icon Affymetrix Yeast Genome S98 Array (ygs98)

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Description
The Saccharomyces cerevisiae SFP1 is required for proper regulation of ribosome biogenesis and cell size in response to nutrients. A mutant deleted for SFP1 shows specific traits among which a slow growth phenotype, which is particularly evident during growth on glucose. To assess the effects of nutrients on the activity of Sfp1 independent by growth rate related feedback we grew an sfp1 mutant and its isogenic reference strain in chemostat cultures, at the same specific growth rate, under glucose/ethanol-limitation. Our data show that Sfp1 is involved in the modulation of cell size and RiBi gene expression and that these two functions are differently influenced by nutrients.
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26
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